Key words: peptides, melanin, tanning


Article was published in the SOFW Journal English Edition | 135 | 7-2009 and may be found at www.sofw.com -> SOFW Journal
A new patented tanning peptide has proved to act as a tanning accelerator and long-lasting key active ingredient for tanning formulations by stimulating the skin natural tanning mechanisms. Melatime™ showed to induce cAMP production and stimulate melanogenesis in melanocytes, increasing melanin content in a dose-response manner in human melanocytes in absence of UV radiation, proving its efficacy in vitro as selftanning agent and ensuring a skin nat ural tan which fits the skin constitutive colour.
Under UV-induced conditions, Melatime™ decreased skin luminosity and darkened the skin colour in vivo, demonstrating to stimulate pigmentation intensity. In addition, the peptide also showed to be effective in prolonging the suntan two weeks after discontinuing the UV-exposure.
In conclusion, Melatime™ can be regarded as an effective tanning active ingredient for tanning accelerating and longlasting cosmetic formulations, allowing to get a perfect long-lasting sun-kissed skin and shorten UV-exposure times.